Graduates

New Langmuir Manuscript

Holland Lab has a new manuscript out in Langmuir titled: "Aspartic Acid Binding on Hydroxyapatite Nanoparticles with Varying Morphologies Investigated by Solid-State NMR Spectroscopy and Molecular Dynamics Simulation". The paper illustrates the significant impact nanoscale morphology has on biomolecule surface binding and organization. The study was led by recent lab PhD graduate and now lab post-doc, Yuan Li. Yuan used a bevy of SSNMR methods to structurally characterize aspartic acid adsorbed to HAP surfaces which was combined with MD simulations conducted by collaborator, Prof. Chris Lorenz @ King's College London. Excellent agreement was found between experimental SSNMR distance measurements and MD models providing atomistic-level structural insights of the bio-nano interface. This work is support by the National Science Foundation (NSF), Division of Chemistry (CHE). The paper can be found here: https://pubs.acs.org/doi/10.1021/acs.langmuir.4c02880 Yuan created some cool cover art that was published with the article: ...