The Holland Lab explores the molecular structure and dynamics of complex biological and technologically relevant materials. We are interested in scientific problems that lie at the interface of chemistry, biology and materials science including natural materials and synthetic nanoparticles functionalized with biomolecular ligands. Although we use a suite of characterization techniques to understand the systems of interest, the primary focus is on developing and applying nuclear magnetic resonance (NMR) methods and combining NMR data with data collected with other advanced biophysical tools including electron microscopy and optical spectroscopy together with simulation and modeling. A continuing theme in our work is linking the role of molecular structure and dynamical features to material properties and biological function.